USP-S Serum
About USP-S Serum
USP-S Serum features a digital camouflage-style pattern layered in metallic red, olive, and gray over a reflective chrome base, giving the silenced pistol a glossy, industrial look. Compared with many USP-S skins that rely on illustrated artwork or clean single-tone finishes, Serum stands out through its shifting metallic finish and abstract patterned treatment.
Release & Source
The USP-S Serum can be found in the CS:GO Weapon Case 2.
Float Range & Wear
The USP-S Serum cannot drop in Well-Worn, Battle-Scarred. The minimum float is 0, making Factory New the best available condition. The maximum float is 0.38, with Field-Tested being the worst available condition.
The USP-S Serum is a Classified-tier skin with an estimated drop chance of ~3.2%, making it one of the rarest USP-S skins in CS2.
Popularity
Community Rating
Frequently Asked Questions
USP-S Serum has a chrome base with a blue-grey digital finish, so cleaner metallic and cool-toned stickers fit it best. Good options include Team LDLC.com (Holo) Cologne 2014, Kjaerbye (Foil) Atlanta 2017, North (Foil) Atlanta 2017, and Cloud9 (Holo) DreamHack 2014. If you want a simpler craft, matching 3x or 4x blue team holos keeps the pattern readable instead of covering it completely.
Yes, USP-S Serum is available in StatTrak because it can come from the CS:GO Weapon Case 2 in StatTrak form. That gives you both regular and StatTrak versions, with the same Serum finish applied to the USP-S. On the market, StatTrak examples are usually less common than standard ones, especially in cleaner wear tiers.
USP-S Serum stands out because it uses a metallic, chrome-based digital pattern rather than a flat painted finish. Compared with USP-S Blueprint, Guardian, or Cyrex, Serum looks more reflective and more patterned, with a cooler silver-blue palette. It also comes from an older case, which makes it feel more tied to early CS:GO skin design.
For a coordinated blue loadout, pair USP-S Serum with M4A1-S Blue Phosphor, AK-47 Frontside Misty, AWP Sun in Leo, and MP9 Cobalt Paisley. If you want a more metallic look, Desert Eagle Cobalt Disruption and FAMAS Pulse also fit the silver-blue tone well. These skins keep the loadout in the same cold color range without clashing with Serum’s reflective finish.

